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KMID : 0043319960190060562
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Archives of Pharmacal Research
1996 Volume.19 No. 6 p.562 ~ p.565
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Photoreactivity of Anthraquinones for the Analysis of Ginsenosides Using Photoreduction Fluorescence Detection-HPLC
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Park Man-Ki
Kim Bak-Kwang
Park Jeong-Hill
Shin Young-Geun
Cho Kyung-Hee
Do Young-Mi
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Abstract
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The photoreactivity of twelve anthraquinone derivatives was examined to evaluate its usefulness as a photo-reagent for the analysis of ginsenosides using photoreduction fluorescence (PRF) detection method. Among the tested compounds, 2-tert-butylandthraquinone (TBAQ), 2-chloroanthraquinone (CAQ) and anthraquinone (AQ) showed good characteristics as photoreagents. The detection limits of ginsenoside PRF-HPLC method using TBAQ, CAQ or AQ as a photo-reagent were found to be ca. 35 ng, 50 ng and 50 ng, respectively.
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KEYWORD
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Anthraquinone, derivatives, Photoreduction fluorescence detection, Analysis of ginsenoside, HPLC chemical lonization
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